The GenTAC Alliance is a division of The Marfan Foundation.
The GenTAC Alliance builds upon the successes of the GenTAC Registry, which enrolled and followed participants from 2006 to 2016.
The Alliance aims to identify knowledge gaps in the treatment of genetic aortic and vascular conditions; convene researchers and healthcare professionals working in this space; increase the understanding of these conditions by healthcare professionals, leading to better patient outcomes worldwide; and accelerate the pace of research focused on these conditions.
Featured Events & Content
November 13: Integrating Mental Health Screening into Aortopathy Care
Join the GenTAC Alliance for an upcoming webinar, “Integrating Mental Health Screening into…
Highlights from Tromsø Aorta 2024
On October 15, Dr. Kim Eagle, GenTAC chair and director of the Frankel Cardiovascular Center at…
Aortic Dissection Awareness Week
Aortic Dissection Awareness Week is a time when we especially focus on helping everyone understand…
GenTAC Aortic Summit
The GenTAC Aortic Summit is one of the premier meetings in the world focused on sharing knowledge…
Management of Aortopathy in Children
On August 12, 2024, the American Heart Association (AHA) published the first comprehensive…
Single-cell Transcriptomics Webinar
The GenTAC Alliance Basic and Translational Science Working Group held a webinar titled,…
Sexual Dimorphism in Thoracic Aortic Disease Webinar
The GenTAC Alliance Basic and Translational Science Working Group held a webinar titled, “Sexual…
VEDS CME/CNE Course Available
An online Vascular Ehlers-Danlos Syndrome (VEDS) CME course is available to medical professionals…
Things Every ED Pro Should Know About Aortic Emergencies
In this two-minute video, Dr. Kim Eagle, chair of the GenTAC Alliance, talks about the three…
Upcoming & Past Webinars
November 13: Integrating Mental Health Screening into Aortopathy Care
In this webinar scheduled for November 13 at 7:00 p.m. Eastern, Siddharth Prakash, MD, PhD, and Sharon Zachariah, BS of UTHealth Houston, will discuss their innovative approach to incorporating mental health screenings into TAD care. They will share the outcomes of this program and discuss how it can be standardized in clinics worldwide to improve mental health outcomes for individuals with TAD.
Highlights from Tromsø Aorta 2024
On October 15, 2024, Dr. Kim Eagle, GenTAC chair and director of the Frankel Cardiovascular Center at University of Michigan, shared key insights from the 8th GenTAC Aortic Summit held in Tromsø, Norway in August.
Molecular and cellular dynamics in aortic diseases: New insights from single-cell transcriptomic studies
In this webinar from March 7, 2024, speakers discussed the latest discoveries gained from single-cell transcriptomic studies, focusing on the changes in aortic cells and inflammatory cells during the development of aortic aneurysms and aortic dissection.
Sexual Dimorphism in Thoracic Aortic Disease
Webinar speakers present evidence of sexual dimorphism in heritable thoracic aortic disease in both animal models and humans.
Accessing GenTAC Data and Biospecimens Using BioLINCC
This webinar covers the process for accessing data and biospecimens from the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) available through BioLINCC.
Exploiting Advantages of the Zebrafish Model for the Study of Aortopathies
This webinar covers recent progress with mutant zebrafish models, including their ability to provide clinically pertinent clues regarding true pathogenecity.
Transcriptional and Epigenetic Factors in the Generation of Thoracic Aortic Disease
Experts in the field of epigenetics and transcriptional mechanics of the ascending aorta discuss their research and its implications in the generation of thoracic aortic disease (TAD) in patients with a bicuspid aortic valve (BAV).
iPSC Models of Thoracic Aortopathies: Possibilities and Challenges
This webinar provides state of the art examples of using induced pluripotent stem (iPS) cells for modeling thoracic aortic disease in Loeys-Dietz syndrome and Marfan syndrome.
Machine Learning and Cardiovascular Disease: New Tools for Diagnosis and Clinical Risk Prediction
This webinar covers recent advances related to the application of artificial intelligence (AI) to improve our understanding of aortic diseases.
